| #1 | Spartanburg Community College | Spartanburg, SC | ~$2,000/yr (est.) | Rural upstate learners avoiding debt | |
Spartanburg Community College's Practical Nursing Diploma is delivered on campus at the Cherokee County Campus in Gaffney, with day, night, and weekend sections to support working students. The college reports an expansion to about 100 LPN students per year, and graduates carry among the lowest median loan debt in this ranking. The institution's overall graduation rate is modest, so treat that figure as a school-wide measure rather than LPN-specific outcomes. - ACEN candidacy status, not fully accredited yet
- Day, night, and weekend sections at Cherokee County Campus
- Union County option with compressed 7.5-week nursing courses
- TEAS required; no minimum score, higher scores break ties
- Median debt around $6,500, one of the lowest in this ranking
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| #2 | Florence-Darlington Technical College | Florence, SC | $5,000 – $7,000/yr (est.) | Pee Dee students wanting affordable entry | |
This campus-based Practical Nursing diploma in Florence is built around a 16-month, 48-credit sequence and local clinical rotations in the Pee Dee region. The net price after aid is one of the lowest among ranked SC programs, making it a practical choice for cost-conscious students. As with all schools listed, the overall graduation rate reflects the whole institution rather than the LPN cohort. - 16-month, 48-credit curriculum
- TEAS entrance exam required
- Clinical rotations at Pee Dee regional healthcare sites
- Net price after aid around $2,000
- Career Talk attendance mandatory for admission
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| #3 | Orangeburg Calhoun Technical College | Orangeburg, SC | $5,000 – $8,000/yr (est.) | Working adults needing flexible scheduling | |
OCtech's Practical Nursing diploma is a campus-based program with both Traditional and FLEX schedules, serving Orangeburg and Calhoun counties. The program reports a 94% licensure pass rate and 100% job placement, with fall and spring start dates. The college's overall graduation rate is a school-wide figure, not specific to nursing. ACEN accredited - ACEN accredited
- Traditional and FLEX delivery models
- 94% NCLEX-PN licensure pass rate
- 100% job placement rate reported
- Fall and spring start dates
- Early hands-on clinical exposure emphasized
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| #4 | Trident Technical College | Charleston, SC | $5,000 – $9,000/yr (est.) | | |
Trident Technical College in Charleston offers a three-semester Practical Nursing diploma that combines lab simulation with supervised clinical shifts. It has the lowest net price after aid in this ranking, and graduates can ladder into the Associate Degree Nursing program. No high school diploma is required to apply, though admission remains competitive. - Three-semester, 43-credit sequence
- Lowest net price after aid in this ranking
- Pathway into Associate Degree Nursing
- No high school diploma required to apply
- ACEN accredited
- Competitive admission with GPA, entrance exam, or Pre-Nursing certificate options
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| #5 | Northeastern Technical College | Cheraw, SC | $7,000/yr (est. net price) | | |
NETC's Practical Nursing diploma in Cheraw can be completed in two semesters plus one summer term, making it one of the faster pathways in this list. The program serves Chesterfield, Dillon, and Marlboro counties and includes an LPN-to-ADN transition option. Note that the college's overall graduation rate is low, but that reflects the full student body rather than the nursing program. - Complete in two semesters plus one summer term
- 48 total credit hours
- TEAS required; competitive admissions
- LPN-to-ADN transition pathway available
- Two-attempt limit for nursing program admission
- Criminal background check required after acceptance
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| #6 | Aiken Technical College | Graniteville, SC | under $5,000/yr (est.) | | |
Aiken Technical College's Licensed Practical Nursing program is a full-time, roughly 1.5-year diploma based in Graniteville. It reports a 100% job placement rate, and among this ranking, the institution's median graduate earnings are the highest. Admission is competitive, selecting only the top 16 applicants per cohort. - 1.5-year full-time format
- ACEN and SC Board of Nursing accredited
- TEAS entrance exam required
- Only top 16 students selected per cohort
- 100% job placement rate reported
- Estimated total program tuition $9,200 before aid
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| #7 | York Technical College | Rock Hill, SC | ~$6,000/yr (est.) | | |
York Technical College's Practical Nursing diploma is delivered at the Chester campus, with clinical rotations across York, Chester, and Lancaster counties. The program uses a first-qualified, first-served waitlist rather than a points-based ranking, and its median loan debt is among the lower figures in this list. The college's overall graduation rate is a school-wide measure, not LPN-specific. ACEN accredited - Delivered at Chester campus
- Clinical rotations across York, Chester, and Lancaster counties
- First-qualified, first-served limited enrollment
- TEAS or placement testing accepted for entry
- ACEN accredited
- Median debt around $7,000
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| #8 | Williamsburg Technical College | Kingstree, SC | ~$10,000/yr (est.) | | |
Williamsburg Technical College's Health Science Practical Nursing diploma is a 40-week, 48-credit program in Kingstree, making it the shortest in this ranking. The structure combines classroom, lab, and clinical rotations in rural healthcare settings. The college's overall graduation rate is very low, so prospective students should ask the program directly for nursing-specific outcomes. - 40-week, 48-credit format
- TEAS score of 60+ required
- Minimum 2.0 GPA
- Clinical rotations in medical-surgical, obstetric, pediatric, geriatric, and community settings
- NCLEX-PN eligibility upon completion
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| #9 | Horry-Georgetown Technical College | Conway, SC | ~$4,000/yr (est.) | | |
Horry-Georgetown Technical College's Nursing PN Diploma serves the Conway and Myrtle Beach area, with classes at Georgetown and Grand Strand campuses. The institution reports the highest overall graduation rate among schools in this ranking, though that figure covers all students, not just LPN completers. The program uses a first-qualified admission process with limited seats. ACEN accredited - ACEN accredited
- 48 total credit hours
- 2.5 minimum GPA for admission
- TEAS entrance exam required
- First-qualified admission with limited seats
- Clinical rotations across coastal Horry and Georgetown counties
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| #10 | Midlands Technical College | West Columbia, SC | $5,000 – $15,000/yr (est.) | | |
Midlands Technical College's Practical Nursing diploma in West Columbia offers three start dates per year, more than most SC programs, plus a simulation lab and local clinical placements. The program reports a 90% licensure pass rate and 96% job placement. The college's overall graduation rate is the lowest in this ranking, so treat it as a school-wide indicator rather than LPN performance. ACEN accredited - Three start dates per year (fall, spring, summer)
- ACEN accredited
- 44 total credit hours
- 90% licensure pass rate reported
- 96% job placement rate reported
- Pathway to LPN-to-ADN transition
- State-of-the-art simulation lab and local clinical placements
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