| #1 | Citadel Military College of South Carolina | Charleston, SC | $13,000 – $39,000/yr | Military and career-change learners | |
The Citadel, located in Charleston just a short drive from North Charleston, offers two pathways to a BSN: a traditional daytime cadet program and an evening hybrid track for college graduates and working adults. The college draws on major Charleston-area health systems for clinical rotations and has a dedicated military pipeline, making it a strong local choice for veterans, active-duty personnel, and career changers. Recent NCLEX pass rates have climbed into the mid-80% range, and the low student-faculty ratio ensures close mentorship. The Citadel’s focus on leadership and evidence-based practice prepares graduates for high-demand roles in the regional healthcare market. - Full-time campus-based program with a leadership emphasis
- Accepts approximately 24 cadets per year with competitive admission
- Requires a 3.0 GPA and B or better in math and science prerequisites
- Clinical placements at Trident-area hospitals including MUSC and Roper St. Francis
- Integrates research opportunities and evidence-based projects
- Prepares for NCLEX-RN with a curriculum spanning fundamentals to special populations
- Veteran applicants receive additional admission consideration
- Evening hybrid format designed for adult students and working professionals
- Five-semester completion pathway for those with prior college credits
- Combines online coursework with evening clinical experiences in Charleston
- Requires a 3.0 GPA and strong grades in math and science prerequisites
- Early decision deadline October 1, final deadline March 1
- Emphasizes quality nursing education with flexible scheduling
- Graduates are eligible for the same NCLEX-RN licensure exam
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| #2 | Clemson University | Clemson, SC | $20,000 – $25,000/yr | Hands-on clinical immersion seekers | |
Clemson University’s BSN program is an eight-semester, campus-based degree known for high NCLEX pass rates and a statewide clinical network that includes Lowcountry sites. Students gain early exposure to nursing concepts through high-fidelity simulation labs and diverse rotations, supported by small class sizes and personalized mentorship. Although the main campus is in the Upstate, Clemson actively recruits from all SC counties and places graduates in hospitals and health systems across the state, including the Charleston metro. The program’s strong reputation and robust scholarship options make it a competitive pick for in-state students aiming for a comprehensive university experience. - Eight-semester program blending theory with extensive clinical practice
- NCLEX pass rates consistently above national averages
- Early exposure to nursing concepts beginning in the first year
- High-fidelity simulation center and diverse hospital rotation sites
- Small faculty-to-student ratio for individualized mentorship
- Scholarships and need-based financial aid available
- Prepares graduates for entry-level registered nursing positions
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| #3 | University of South Carolina | Columbia, SC | $23,000/yr | High-achieving academic track students | |
The University of South Carolina’s flagship nursing program in Columbia is a top-tier BSN with a top 1% NCLEX pass rate nationally and two NLN Center of Excellence designations. The curriculum balances core classes with state-of-the-art simulation training, and students can sometimes complete clinical rotations in Lowcountry facilities through USC’s statewide network. For career changers without a nursing background, a hybrid Direct Entry MSN offers an accelerated path to RN licensure. USC’s strong alumni placement and high 10-year graduate earnings make it a compelling option for North Charleston residents willing to relocate for school and return to work in the coastal region. - Campus-based BSN with a curriculum leading to a top 1% NCLEX pass rate
- Designated a National League for Nursing Center of Excellence twice
- State-of-the-art simulation lab and over $20 million in grant-funded research
- Focus on leadership, community health, and evidence-based practice
- Clinical rotations available through a statewide network, including coastal sites
- Four-year program with strong faculty support and innovative teaching methods
- Hybrid Master’s entry program for non-nursing college graduates
- Prepares students for RN licensure and advanced nursing roles
- Spring admissions with prerequisite courses in anatomy, physiology, and microbiology
- Requires a personal goal statement, three references, and a resume
- Prerequisite coursework must be completed with a C or better within five years
- Offers a fast-track entry to practice with a Master of Science in Nursing
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| #4 | Bob Jones University | Greenville, SC | ~$17,000/yr (est.) | | |
Bob Jones University in Greenville offers a Christ-centered BSN that emphasizes nursing as a calling, with six semesters of clinical experience, more than many comparable programs. The school boasts a 98% NCLEX-RN pass rate and a fast-track option that allows completion in as few as three years. Students gain hands-on skills in an accredited simulation center and can participate in medical mission trips, with graduates recruited by faith-based hospitals throughout South Carolina, including those in the Charleston area. Competitive admission requires a 2.75 GPA and the ATI TEAS exam. - Three-year fast-track option for efficient degree completion
- Six semesters of clinical rotations, exceeding many traditional BSN programs
- Accredited simulation center with high-fidelity patient simulators
- 98.0% first-time NCLEX-RN pass rate, well above state and national averages
- Faith-integrated curriculum with opportunities for medical mission trips
- Concentrations available in Medical Missions or Public Health Nursing
- Competitive admission: minimum 2.75 GPA and ATI TEAS exam required
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| #5 | Anderson University | Anderson, SC | $24,000/yr | | |
Anderson University’s traditional BSN is a four-year, campus-based program that pairs a holistic nursing philosophy with access to a cadaver lab and modern simulation center. Students complete 123 credit hours with clinical placements at diverse Upstate healthcare facilities, preparing for the NCLEX-RN and a career in registered nursing. The program integrates a Christian worldview and offers fall and spring start dates, along with scholarships and financial aid for eligible students. Graduates are recruited by health systems across South Carolina, providing a pathway to lowcountry employment after licensure. - 123 credit hours of comprehensive nursing education over four years
- Hands-on training in a state-of-the-art simulation center and cadaver lab
- Christ-centered curriculum emphasizing holistic patient care
- Clinical rotations at multiple Upstate South Carolina hospitals
- Requires SAT, ACT, or CLT scores plus official transcripts and two essays
- Fall and spring start dates with scholarship opportunities available
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| #6 | Spartanburg Community College | Spartanburg, SC | ~$2,000/yr (est.) | | |
Spartanburg Community College’s ACEN-accredited ADN program offers a low-cost, campus-based route to registered nursing with a net price under $2,500 per year. The curriculum focuses on holistic care across the lifespan and prepares graduates for the NCLEX-RN. While clinical sites are concentrated in the Spartanburg area, the degree’s transferability allows SCC graduates to enroll in online RN-to-BSN programs offered by MUSC and other universities that serve the Charleston region, making it a budget-friendly starting point for North Charleston students open to relocating for two years. - ACEN-accredited ADN program with a comprehensive nursing curriculum
- Campus-based format with clinical experiences in local Spartanburg facilities
- Focus on holistic care, health promotion, and disease prevention across ages
- Prepares students to take the NCLEX-RN and become registered nurses
- Affordable net price and low median graduate debt
- Strong articulation with RN-to-BSN programs across South Carolina
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| #7 | York Technical College | Rock Hill, SC | ~$6,000/yr (est.) | | |
York Technical College’s associate degree nursing program in Rock Hill provides a solid foundation for RN licensure through classroom instruction and clinical practice in the Catawba region. The ACEN-accredited curriculum emphasizes critical thinking, professional behaviors, and direct patient care across the lifespan. With a net price under $6,000, it is one of the more affordable pathways into nursing. Graduates can later transition to fully online RN-to-BSN programs that are popular with Charleston-area nurses, though the main campus is a significant distance from North Charleston. - ACEN-accredited ADN program focused on acute and chronic care
- Campus-based learning with clinical rotations in Rock Hill-area facilities
- Stresses critical thinking, communication, and professional nursing behaviors
- Prepares graduates for the NCLEX-RN and immediate entry into practice
- Financial aid options available to eligible students
- Meets South Carolina Board of Nursing education standards
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| #8 | Coastal Carolina University | Conway, SC | $10,000 – $15,000/yr | | |
Coastal Carolina University’s BSN program in Conway blends liberal arts with evidence-based nursing practice, emphasizing health promotion, patient safety, and leadership. Students complete 120 credit hours with hands-on clinical experiences in coastal community settings, which can offer relevant population-health insights for those interested in similar environments like the Charleston area. The university’s affordable net price and ACEN accreditation make it an attractive in-state option, though it is located in the Myrtle Beach region rather than the immediate North Charleston metro. - Four-year BSN program with a liberal arts foundation
- ACEN-accredited with a curriculum emphasizing evidence-based practice
- 120 credit hours including clinical rotations in coastal community sites
- Requires SAT, ACT, or TEAS scores for admission
- Covers health promotion, disease prevention, and leadership skills
- Prepares graduates for the NCLEX-RN and diverse entry-level nursing roles
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| #9 | Horry-Georgetown Technical College | Conway, SC | ~$4,000/yr (est.) | | |
Horry-Georgetown Technical College’s ADN program is an affordable, campus-based option with two admission pathways and a strong NCLEX preparation focus. With campuses in Conway, Georgetown, and the Grand Strand, it serves the northern coast of South Carolina. The curriculum spans fundamentals, pharmacology, and patient care across 68 credit hours. Graduates are eligible to take the NCLEX-RN and can later pursue online RN-to-BSN programs, which can position them for nursing roles in the Charleston market after gaining initial experience and licensure. - ACEN-accredited ADN program with classroom and clinical training
- Two admission pathways with TEAS score of 75+ and a minimum 2.75 GPA
- 68 credit hours covering fundamentals, pharmacology, and patient care
- Clinical experiences at Georgetown and Grand Strand healthcare facilities
- Requires CPR certification, background check, and health record
- Graduates are prepared for the NCLEX-RN and registered nursing practice
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| #10 | University of South Carolina-Upstate | Spartanburg, SC | ~$14,000/yr (est.) | | |
USC Upstate’s hybrid BSN in Spartanburg combines online coursework with in-person clinical rotations at regional medical centers, offering flexibility for students who balance other responsibilities. The program reports a 97% first-time NCLEX pass rate and is recognized as a key supplier of RNs for the state. While not based in the Lowcountry, the hybrid format and statewide clinical reach can accommodate students willing to travel for labs and clinicals, and graduates are in high demand across South Carolina, including the Charleston area. - Hybrid BSN combining online didactic courses with in-person clinicals
- 97% first-time NCLEX pass rate among recent graduates
- 126 credit hours with clinical rotations at regional Upstate medical centers
- State-of-the-art Simulation Center for hands-on skill development
- Opportunities for summer study abroad and a dual degree in biology
- Graduates are highly sought-after by employers throughout South Carolina
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