| #1 | Francis Marion University | Florence, SC | $11,000 – $22,000/yr (est.) | Rural Pee Dee nurses seeking hybrid study | |
Francis Marion University in Florence offers a hybrid RN to BSN for South Carolina-licensed registered nurses who hold an ADN or nursing diploma. The program emphasizes leadership, community health, and evidence-based practice, with clinical and project work tied to Pee Dee area hospitals and rural or underserved populations. The nursing department holds CCNE accreditation and an NLN Center of Excellence designation. School-wide, the graduation rate is about 43%, while median earnings are about $43,900 and median debt near $27,000 for students ten years after entering. CCNE accredited - CCNE accredited
- NLN Center of Excellence for faculty expertise
- Curriculum covers leadership, community health, evidence-based practice
- Flexible hybrid options for working nurses
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| #2 | University of South Carolina-Upstate | Spartanburg, SC | ~$14,000/yr (est.) | Working RNs needing multiple start dates | |
The University of South Carolina Upstate in Spartanburg offers a hybrid RN to BSN that full-time students can complete in about one year. It includes 32 nursing credit hours, with classes online or at the Greenville campus one day a week, and grants in-state tuition to all online students. Highlights include an RN-MSN pathway, credit for prior ADN coursework, and five start dates each year. School-wide, the graduation rate is about 43%, while median earnings are about $48,600 and median debt near $22,300. CCNE accredited - Complete in as few as 12 months
- 32 nursing credit hours
- Online or Greenville campus one day weekly
- In-state tuition for all online students
- RN-MSN pathway available
- Credit for prior ADN courses
- Five start dates per year
- Full-time and part-time plans
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| #3 | University of South Carolina Aiken | Aiken, SC | $11,000 – $21,000/yr (est.) | Budget-conscious online RN completers | |
The University of South Carolina Aiken offers a fully online RN to BSN built for working nurses. The CCNE-accredited program spans 31 credit hours and can be completed in as few as 12 months, with a total program tuition of $9,486 and per-credit cost of $306. Students complete 40 clinical hours and a capstone, and benefit from multiple start dates and the same faculty as the on-campus program. School-wide, the graduation rate is about 40%, while median earnings are about $45,600 and median debt near $24,300. CCNE accredited - $9,486 total program tuition
- $306 per credit hour
- Finish in as few as 12 months
- 31 credit hours across 9 courses
- 40 clinical hours required
- 2.5 minimum GPA for admission
- Multiple start dates each year
- 100% online format
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| #4 | University of South Carolina | Columbia, SC | ~$23,000/yr (est.) | | |
The University of South Carolina in Columbia offers an online RN to BSN through its College of Nursing. The 12-month program starts in the fall and is tailored to practicing RNs, with emphasis on leadership, management, and clinical reasoning. Students have access to the university's broader resources and expert nursing faculty. School-wide, the graduation rate is about 79%, while median earnings are about $62,200 and median debt near $21,500, reflecting the flagship's strong salary outcomes. CCNE accredited - Complete in as few as 12 months
- Fall start date
- Designed for working RNs' schedules
- Focus on leadership and management
- Access to university-wide resources
- Taught by College of Nursing faculty
- Tailored for practicing RNs
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| #5 | Coker University | Hartsville, SC | $20,000/yr (est. net price) | | |
Coker University in Hartsville offers an online RN-BSN completion program for registered nurses with an ADN or diploma. The program includes 30 credit hours across nine courses and is designed to be completed in four semesters, with a 3.0 GPA and active unencumbered RN license required. It carries NLN CNEA pre-accreditation and is especially transfer-friendly for graduates of South Carolina technical and community colleges. School-wide, the graduation rate is about 40%, while median earnings are about $40,100 and median debt near $26,000. - 4-semester completion
- 30 credit hours and 9 courses
- 3.0 GPA minimum
- Active unencumbered RN license required
- Fully online delivery
- NLN CNEA pre-accreditation
- Transfer-friendly from ADN programs
- Prepares for management and specialized roles
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| #6 | Columbia International University | Columbia, SC | $26,000/yr (est. net price) | | |
Columbia International University in Columbia offers an online RN to BS in Nursing in a faith-based environment. The CCNE-accredited program is transfer-friendly for ADN-prepared nurses and emphasizes compassion, integrity, patient care, and clinical decision-making. It offers guaranteed interviews at select graduate schools for students who plan to continue into advanced nursing education. School-wide, the graduation rate is about 47%, while median earnings are about $39,000 and median debt near $20,000. CCNE accredited - CCNE accredited
- Faith-based learning environment
- Transfer-friendly for ADN and prior credits
- Guaranteed interviews at select graduate schools
- Focus on compassion and integrity
- Prepares for leadership roles
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| #7 | South University-Columbia | Columbia, SC | $25,000 – $30,000/yr (est.) | | |
South University's Columbia campus offers a hybrid RN to BSN for registered nurses, with the option to combine campus and online classes. Clinical, practicum, or externship portions require in-person attendance, and the program is designed to prepare nurses for NCLEX and state licensure. Prospective students should ask about program-specific completion outcomes, as the school-wide graduation rate is lower than most other options on this list. School-wide, the graduation rate is about 23%, while median earnings are about $34,400 and median debt near $26,100. - Combine campus and online learning
- Clinical, practicum, or externship requires in-person
- Prepares nurses for NCLEX and licensure
- Columbia, SC campus location
- Online classes available
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| #8 | Newberry College | Newberry, SC | ~$22,000/yr (est.) | | |
Newberry College in Newberry offers a fully online RN-to-BSN completion track designed for working nurses. The CCNE-accredited program requires 33 credit hours, can be finished in as few as 12 months, and costs $405 per credit with no application fee. It is eligible for the South Carolina Tuition Grant, making it a strong value for in-state residents. School-wide, the graduation rate is about 45%, while median earnings are about $48,000 and median debt near $26,800. CCNE accredited - $405 per credit hour
- 33 credit hours required
- Complete in as few as 12 months
- No application fee
- South Carolina Tuition Grant eligible
- CCNE accredited
- Designed for working nurses
- Active RN license required
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