Top Nurse Practitioner Programs in South Dakota

Top Nurse Practitioner Programs in South Dakota
Jake Flannigan, NP

Jake Flannigan, NP

July 15, 2025

South Dakota’s NP programs train RNs for advanced practice in both urban centers like Sioux Falls and rural clinics statewide. CCNE‑accredited MSN and DNP tracks, primarily at the University of North Dakota and North Dakota State University, offer specialties such as Family and Psychiatric‑Mental Health NP. Graduates are eligible for national certification and South Dakota APRN licensure with full prescriptive authority, with an emphasis on serving the state’s rural healthcare needs.

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2026 Top Nurse Practitioner Programs in South Dakota

Aspiring nurse practitioners in South Dakota have access to exceptional educational pathways that prepare them for rewarding healthcare careers. TopNursing.org has carefully evaluated and ranked the state's top nursing programs based on academic quality, clinical training opportunities, faculty expertise, and student success rates. Our comprehensive analysis highlights the most prestigious institutions that offer comprehensive nurse practitioner degree tracks, ensuring students receive cutting-edge medical education. These programs equip future healthcare professionals with advanced clinical skills, specialized knowledge, and the practical experience needed to excel in diverse medical settings across South Dakota. Whether students aim to work in rural clinics, urban hospitals, or specialized healthcare environments, these top-ranked programs provide the foundation for a successful nursing career. Learn more about our ranking methodology.
#1

Mount Marty University

Yankton, SD - Private 4-year - mountmarty.edu

Master's - Master of Science in Nursing - Family Nurse Practitioner

Online & Campus Based - Visit Website

Mount Marty University's Master of Science in Nursing Family Nurse Practitioner track provides comprehensive advanced practice nursing education with a distinctive rural healthcare focus. The hybrid program spans 50 credits and emphasizes holistic, evidence-based patient care across diverse populations. Designed exclusively for licensed RNs, students develop advanced clinical expertise through rigorous academic training and extensive hands-on experiences. With a minimum 3.0 GPA requirement and 720 clinical hours, graduates are uniquely prepared to address complex healthcare challenges in primary care settings. The CCNE-accredited program integrates post-graduate certification options and prioritizes comprehensive patient management strategies.

  • 50 total credit program
  • 3.0 GPA minimum requirement
  • CCNE accredited program
  • RN licensure required
  • 720 total clinical hours
  • Full-time student status
  • Post-graduate certification option
  • Rural healthcare focus
  • Advanced practice preparation
  • Holistic patient care approach

Master's - Master of Science in Nursing

Concentration: Psychiatric Mental Health Nurse Practitioner - Online Learning - Visit Website

Mount Marty University's Psychiatric Mental Health Nurse Practitioner program delivers comprehensive two-year online training for advanced practice nurses. The 50-credit curriculum encompasses 750 clinical hours, focusing on evidence-based psychiatric care and advanced mental health interventions. Students develop sophisticated skills in diagnosing and treating psychological conditions through integrated pharmacotherapy and psychotherapy approaches. Emphasizing compassionate care in rural and underserved settings, the program integrates Catholic Benedictine values while preparing graduates to address complex mental health challenges across diverse populations.

  • 50 total credits required
  • 750 clinical practice hours
  • Evidence-based psychiatric care
  • Rural healthcare focus
  • Advanced pharmacotherapy training
  • Psychotherapy skill development
  • Comprehensive mental health assessment
  • Catholic Benedictine values integration

Master's - Master of Science in Nursing Family Nurse Practitioner

Campus Based - Visit Website

Mount Marty University's campus-based Master of Science in Nursing Family Nurse Practitioner program provides comprehensive advanced practice preparation. Blending in-person and online learning, the curriculum emphasizes rural health, disease prevention, and compassionate care through Catholic Benedictine values. Students receive extensive training in advanced pharmacology, physical assessment, and lifespan patient management. The CCNE-accredited program offers flexible learning options while maintaining rigorous academic standards. Graduates are equipped with advanced clinical skills, positioning them to deliver high-quality primary care in diverse healthcare environments.

  • Campus-based program
  • Focus on rural health
  • Integrates Benedictine values
  • Advanced pharmacology included
  • Physical assessment training
  • Disease prevention emphasis
  • Compassionate care focus
  • Clinical hours required
  • Accredited by CCNE
  • Flexible learning options

Graduate Certificate - Post-Graduate APRN Certificate

Concentration: Family Nurse Practitioner - Online & Campus Based - Visit Website

Mount Marty University's Post-Graduate APRN Certificate in Family Nurse Practitioner offers specialized advanced practice training for experienced registered nurses. Requiring a minimum 3.0 GPA, current RN licensure, and one year of professional experience, this hybrid program provides comprehensive primary healthcare preparation. The CCNE-accredited curriculum emphasizes evidence-based practices, holistic patient care, and advanced clinical skills development. Students gain expertise in managing acute and chronic health conditions while exploring multiple program entry tracks. Professional recommendations and Basic Life Support certification complement the rigorous academic training, positioning graduates as highly competent family healthcare professionals.

  • CCNE Accredited Program
  • 3.0 GPA Minimum Requirement
  • Minimum 1 Year RN Experience
  • Advanced Clinical Skills Training
  • Holistic Patient Care Focus
  • Evidence-Based Practice Curriculum
  • Primary Healthcare Specialization
  • Professional Recommendation Required
  • Basic Life Support Certification
  • Multiple Program Entry Tracks
Show 3 More Programs ˅
#2

Augustana University

Sioux Falls, SD - Private 4-year - augie.edu

Graduate Certificate - Post-Master's Certificate in Adult-Gerontology Acute Care Nurse Practitioner

Online Learning - Visit Website

Augustana University's Post-Master's Certificate in Adult-Gerontology Acute Care Nurse Practitioner offers a specialized online pathway for experienced nurses seeking advanced clinical expertise. This CCNE-accredited program enables working professionals to enhance their acute care skills through a comprehensive 15-month curriculum. Featuring two intensive 4-day campus immersion sessions, the program prepares nurses to provide complex medical care in challenging inpatient environments. Candidates must possess a minimum 3.25 GPA, two years of professional nursing experience, and an active RN license. Upon completion, graduates are well-positioned to take the AG-ACNP certification exam and advance their healthcare leadership capabilities.

  • Online flexible curriculum
  • 15-month certificate program
  • CCNE accredited program
  • Two 4-day campus immersions
  • Prepares for AG-ACNP certification
  • Requires 2+ years nursing experience
  • Specializes in acute care practice

Doctorate - Master of Science in Nursing (MSN) with Adult-Gerontology Acute Care Nurse Practitioner (AG-ACNP) track

Online & Campus Based - Visit Website

Augustana University's Master of Science in Nursing delivers a transformative hybrid learning experience tailored for Adult-Gerontology Acute Care Nurse Practitioners. This innovative program combines flexible online coursework with immersive on-campus sessions, allowing working professionals to develop advanced clinical competencies. Spanning approximately 2.5 years, the CCNE-accredited curriculum emphasizes holistic patient care, interprofessional collaboration, and leadership development. Students specializing in AG-ACNP gain comprehensive skills to address complex adult and geriatric healthcare needs. Prerequisites include a BSN, active RN license, and relevant nursing experience, providing a strategic pathway for nurses seeking meaningful career advancement in acute care settings.

  • Hybrid learning model.
  • CCNE accredited program.
  • Specializes in AG-ACNP.
  • 2.5 years to complete.
  • Requires BSN and RN license.
  • Two on-campus immersions.
  • Focuses on acute care.
  • Prepares for leadership roles.
  • Holistic patient care approach.
  • Interprofessional collaboration focus.
Show 1 More Programs ˅
*Source data: IPEDS 2023, compiled by NCES.

Program Curriculum & Length

Length

Curriculum

Advanced Health Assessment
Advanced Pathophysiology
Advanced Pharmacology
FNP Roles & Issues
Clinical Readiness & Practicum Courses

Clinical Rotations

Are Online Nurse Practitioner Programs Available in South Dakota

Programs often use a hybrid format: didactic lectures and discussions delivered online via asynchronous modules and live webinars, with periodic on‑campus intensives for simulation labs and skills workshops. Clinical rotations are arranged locally at approved sites, and some schools offer fully online didactic phases requiring only brief in‑person skill assessments.

2026 Fastest NP Program Options in South Dakota

For nursing professionals seeking to advance their careers quickly in South Dakota, accelerated programs offer an efficient pathway to higher education. These shortest nursing practitioner programs cater to working healthcare professionals who want to minimize time away from their careers while earning advanced credentials. Rapid educational tracks in cities like Sioux Falls and Rapid City enable students to complete their degrees faster, providing flexible learning options that balance professional responsibilities with academic growth. Students can expect comprehensive curriculums that maintain high academic standards while allowing for expedited completion. Understanding the value of time and professional development, these programs strategically design coursework to help nurses transition smoothly into advanced practice roles with minimal disruption to their current work schedules.
School NameHighlightsRetention & Grad Rates
Augustana University
  • Hybrid learning model.
  • CCNE accredited program.
  • Specializes in AG-ACNP.
  • 2.5 years to complete.
  • Requires BSN and RN license.
  • Two on-campus immersions.
  • Focuses on acute care.
  • Prepares for leadership roles.
  • Graduation Rate: 76%
  • Retention Rate: 84%
  • Student to Faculty Ratio: 11:1
Mount Marty University
  • Campus-based program
  • Focus on rural health
  • Integrates Benedictine values
  • Advanced pharmacology included
  • Physical assessment training
  • Disease prevention emphasis
  • Compassionate care focus
  • Clinical hours required
  • Graduation Rate: 61%
  • Retention Rate: 70%
  • Student to Faculty Ratio: 12:1
*From: U.S. Department of Education, IPEDS 2023. https://nces.ed.gov/ipeds/

Admission Requirements

BSN Degree, Competitive GPA 
From regionally accredited institution, around 3.0
Active RN License 
Current and unencumbered
Application Materials 
Official transcripts, personal statement, letters of recommendation
Insurance and Health Requirements 
Professional liability insurance, proof of immunizations
Background Check 
Criminal history screening and drug screening
Clinical Experience 
Typically 1–2 years of RN clinical experience required before clinical placement

Certification and Licensing

Certifying BoardSouth Dakota Board of Nursing – Advanced Practice Section
CertificationActive South Dakota RN license (or NLC multistate privilege) plus national APRN credential with primary-source verification
License Renewal PeriodBiennial renewal on your birth date every two years, with notices sent three months prior
Continuing EducationNo state-mandated CE, maintain the requirements of your national certifier
License Application Fee$100 application fee
Clinical HoursMinimum of 1,040 practice hours as a licensed NP or CNM in the preceding five years
Processing TimeApproximately 4–6 weeks after receipt of a complete application
EndorsementOut-of-state APRNs must hold (or obtain) a South Dakota RN license and submit primary-source verification of APRN credentials

Salary and Job Outlook

Nurse practitioners in South Dakota earn an average of about $120,980 per year, with metropolitan areas like Sioux Falls seeing wages near $121,000 and Rapid City around $116,000. Compensation packages often include benefits such as health insurance, retirement plans, and sometimes rural retention incentives.

Salary & Career OutlookSouth DakotaUSA
Avg Annual NP Salary$115,000$62,340
Avg Hourly Wage$55.29$29.97
90th Percentile Salary>$130,000$80,510
Median Salary$115,000$62,340
10th Percentile Salary<$95,000$47,960
Projected Job Growth (2022–2032)~45%3%
Annual Job Openings~70~54,000

2026 Affordable NP Program Options in South Dakota

Finding an affordable nursing practitioner program in South Dakota can be crucial for healthcare professionals seeking advanced education. With several options across cities like Sioux Falls and Rapid City, students can explore master's, graduate certificate, and doctoral level programs that balance quality education with reasonable tuition. These programs prepare nurses to meet growing healthcare demands while keeping financial barriers low. Investing in an economical nursing education can open doors to specialized roles and enhanced career opportunities throughout the state. Understanding the range of program options and associated costs helps aspiring nurse practitioners make informed decisions about their professional development and future in healthcare.
School NameHighlightsAnnual Estimated Tuition & Fees
Mount Marty University
  • Campus-based program
  • Focus on rural health
  • Integrates Benedictine values
  • Advanced pharmacology included
  • Physical assessment training
  • Disease prevention emphasis
  • Compassionate care focus
  • Clinical hours required
  • $11,400 - $17,100 (Graduate)
Augustana University
  • Hybrid learning model.
  • CCNE accredited program.
  • Specializes in AG-ACNP.
  • 2.5 years to complete.
  • Requires BSN and RN license.
  • Two on-campus immersions.
  • Focuses on acute care.
  • Prepares for leadership roles.
  • $31,900 - $47,800 (Graduate)
*Data source: NCES, IPEDS 2023 institutional survey.

Advancement Pathways

Many NPs pursue a Doctor of Nursing Practice to deepen clinical expertise and qualify for leadership or academic roles. Post‑master’s certificate programs allow adding new specialties, such as acute care or women’s health, without another full degree. PhD pathways open doors to research and faculty positions, while advanced training also supports careers in administration, informatics, policy development, or telehealth leadership.

List of Nurse Practitioner Programs in South Dakota

Jump to City:

Sioux Falls, SD

Augustana University

  • Graduate Certificate - Post-Master's Certificate in Adult-Gerontology Acute Care Nurse Practitioner

    Online Learning - Website

    • Online flexible curriculum
    • 15-month certificate program
    • CCNE accredited program
    • Two 4-day campus immersions
    • Prepares for AG-ACNP certification
    • Requires 2+ years nursing experience
    • Specializes in acute care practice
  • Doctorate - Master of Science in Nursing (MSN) with Adult-Gerontology Acute Care Nurse Practitioner (AG-ACNP) track

    Online & Campus Based - Website

    • Hybrid learning model.
    • CCNE accredited program.
    • Specializes in AG-ACNP.
    • 2.5 years to complete.
    • Requires BSN and RN license.
    • Two on-campus immersions.
    • Focuses on acute care.
    • Prepares for leadership roles.

Yankton, SD

Mount Marty University

  • Master's - Master of Science in Nursing - Family Nurse Practitioner

    Online & Campus Based - Website

    • 50 total credit program
    • 3.0 GPA minimum requirement
    • CCNE accredited program
    • RN licensure required
    • 720 total clinical hours
    • Full-time student status
    • Post-graduate certification option
    • Rural healthcare focus
  • Master's - Master of Science in Nursing Family Nurse Practitioner

    Campus Based - Website

    • Campus-based program
    • Focus on rural health
    • Integrates Benedictine values
    • Advanced pharmacology included
    • Physical assessment training
    • Disease prevention emphasis
    • Compassionate care focus
    • Clinical hours required
  • Master's - Master of Science in Nursing

    Concentration: Psychiatric Mental Health Nurse Practitioner - Online Learning - Website

    • 50 total credits required
    • 750 clinical practice hours
    • Evidence-based psychiatric care
    • Rural healthcare focus
    • Advanced pharmacotherapy training
    • Psychotherapy skill development
    • Comprehensive mental health assessment
    • Catholic Benedictine values integration
  • Graduate Certificate - Post-Graduate APRN Certificate

    Concentration: Family Nurse Practitioner - Online & Campus Based - Website

    • CCNE Accredited Program
    • 3.0 GPA Minimum Requirement
    • Minimum 1 Year RN Experience
    • Advanced Clinical Skills Training
    • Holistic Patient Care Focus
    • Evidence-Based Practice Curriculum
    • Primary Healthcare Specialization
    • Professional Recommendation Required
*Source: IPEDS 2023 survey results, NCES, U.S. Department of Education.