Top LPN Programs in South Carolina

Top LPN Programs in South Carolina
Jake Flannigan, NP

Jake Flannigan, NP

June 4, 2025

Licensed Practical Nurses (LPNs) deliver essential patient care services in South Carolina’s healthcare facilities across hospitals, nursing homes, clinics and home health settings. LPNs work under the supervision of registered nurses and physicians to perform vital sign monitoring and medication distribution as well as assist patients with everyday tasks. LPNs serve as essential healthcare professionals in South Carolina especially in rural and underserved areas where healthcare providers face high demand. LPNs provide dedicated compassionate medical care throughout the lifespan of their patients. 

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2026 Top LPN Programs in South Carolina

At TopNursing.org, we take pride in delivering comprehensive rankings of the best Licensed Practical Nurse (LPN) programs across South Carolina. Our expert team carefully evaluates each nursing program based on critical factors such as student outcomes, faculty credentials, clinical training opportunities, and overall educational quality. South Carolina offers aspiring nurses several outstanding LPN programs that provide rigorous training and prepare students for successful healthcare careers. Whether you're looking to start your nursing journey in Charleston, Columbia, or Greenville, our rankings will help you find the most reputable and competitive LPN programs in the state. These programs not only meet state licensing requirements but also equip students with the essential skills needed to excel in various healthcare settings. Learn more about our ranking methodology.
#1

Central Carolina Technical College

Sumter, SC - Public 2-Year - cctech.edu

Certificate/Diploma - Practical Nursing

Campus Based - Visit Website

Central Carolina Technical College in Sumter, SC, offers a Practical Nursing Diploma in Applied Science, designed to prepare students for a rewarding career in nursing. This 48-semester-hour program equips graduates with the skills to provide compassionate, competent care in structured settings, using critical thinking and technology. Students gain hands-on clinical experience, enhancing their ability to apply nursing principles effectively. Graduates are prepared to sit for the NCLEX-PN, a crucial step towards licensure. The program is approved by the South Carolina Board of Nursing and is a candidate for accreditation by the ACEN. Admission requirements and program details are subject to change to meet state and system standards.

  • 48 semester hours
  • Prepares for NCLEX-PN
  • Approved by SC Board of Nursing
  • Candidate for ACEN accreditation
  • Hands-on clinical experience
  • Focuses on critical thinking
  • Technology in nursing care
  • Caring for diverse populations
  • Structured clinical settings
  • Licensure preparation
#2

Horry-Georgetown Technical College

Conway, SC - Public 2-Year - hgtc.edu

Certificate/Diploma - Nursing - PN Diploma

Campus Based - Visit Website

Horry-Georgetown Technical College's Practical Nursing (PN) Diploma program provides comprehensive healthcare training for aspiring nurses. In just 48 credit hours, students gain essential skills to care for patients across various healthcare settings. The curriculum combines rigorous classroom instruction with hands-on clinical experiences, preparing graduates to take the NCLEX-PN licensing exam. Admission requires meeting specific academic and health criteria, including a minimum 2.5 GPA, prerequisite courses, and passing the TEAS exam. Graduates can pursue careers in hospitals, clinics, doctor's offices, and extended care facilities, with strong employment prospects in the growing healthcare sector.

  • 48 total credit hours
  • Clinical experience included
  • Prepare for NCLEX-PN exam
  • Multiple campus locations
  • Accredited nursing program
  • Diverse healthcare career paths
  • Comprehensive admission requirements
  • Patient-centered care focus
  • Safe healthcare environment training
  • Critical thinking development
#3

Williamsburg Technical College

Kingstree, SC - Public 2-Year - wiltech.edu

Certificate/Diploma - Diploma – Health Science Practical Nursing

Campus Based - Visit Website

Williamsburg Technical College in Kingstree, SC, offers a Diploma in Health Science Practical Nursing, a 48-credit hour program completed in 40 weeks across three semesters. This campus-based program prepares students for the NCLEX-PN examination through classroom instruction, lab practice, and clinical experience in various healthcare settings. Admission requires a TEAS exam score of 60 or higher, a GPA of 2.0, and completion of prerequisite courses. The program emphasizes hands-on learning and teamwork under registered nurses' supervision, ensuring graduates are ready for practical nursing roles.

  • 40-week program duration.
  • 48 credit hours required.
  • Campus-based learning.
  • TEAS exam score of 60+ needed.
  • GPA requirement of 2.0.
  • NCLEX-PN exam eligibility.
  • Clinical experience included.
  • Hands-on learning focus.
  • Teamwork under RN supervision.
  • Prerequisite courses required.
#4

York Technical College

Rock Hill, SC - Public 2-Year - yorktech.edu

Certificate/Diploma - Practical Nursing

Campus Based - Visit Website

York Technical College's Practical Nursing program offers an intensive pathway into healthcare, providing students with comprehensive training to become skilled professional nurses. The program prepares students for direct patient care through rigorous coursework in anatomy, physiology, chemistry, and clinical experiences across diverse medical settings. Graduates are equipped to take the NCLEX-RN licensing examination, with clinical rotations in hospitals, doctor's offices, community health agencies, and long-term care facilities. The program emphasizes hands-on learning, critical thinking, and patient communication skills.

  • Accredited Nursing Program
  • NCLEX-RN Exam Preparation
  • Diverse Clinical Rotation Experiences
  • Located on Chester Campus
  • Limited Enrollment Program
  • Multiple Admission Tracks
  • Comprehensive Clinical Requirements
  • Flexible Clinical Scheduling
  • Approved by SC Board of Nursing
#5

Northeastern Technical College

Cheraw, SC - Public 2-Year - netc.edu

Certificate/Diploma - Applied Science - Practical Nursing

Campus Based - Visit Website

The Practical Nursing program at Northeastern Technical College equips aspiring nurses with essential skills for a vital healthcare career. Students complete a comprehensive 48-semester-hour curriculum combining classroom instruction and clinical training, preparing them to become Licensed Practical Nurses (LPNs). The program focuses on therapeutic, rehabilitative, and preventive care principles applicable across diverse patient populations and healthcare settings. Graduates must pass the National Council Licensure Exam (NCLEX-PN) to obtain licensure, launching their professional nursing journey.

  • 48 semester hours total
  • Classroom and clinical training
  • Two semesters plus summer term
  • NCLEX-PN exam preparation
  • Competitive admissions process
  • Health sciences foundation
  • Nursing team concept training
  • Multiple healthcare settings
  • Prerequisites may be required
*Data source: NCES, IPEDS 2023 institutional survey.

Program Curriculum & Length

Length

Curriculum

Anatomy & Physiology
Nursing Fundamentals
Pharmacology
Medical-Surgical
Maternal Health
Mental Health

Clinical Rotations

Are Online LPN Programs Available in South Carolina

South Carolina does not provide fully online LPN programs because of clinical requirements yet educational institutions provide hybrid programs which combine flexibility with student-centered learning. The hybrid model enables students to take online general education courses together with laboratory work and clinical rotations through in-person attendance. Students who participate in this educational model can maintain their work-life balance while receiving hands-on clinical experience. Several educational institutions provide evening and weekend classes for nursing students to help adult learners achieve their educational goals. 

2026 Fastest LPN Program Options in South Carolina

Aspiring nurses in South Carolina looking to launch their healthcare careers quickly will find several attractive Licensed Practical Nurse (LPN) training opportunities across the state. With the shortest program options available, students in major regions like Charleston, Columbia, and Greenville can complete their professional training in a remarkably efficient timeframe. These condensed programs prioritize essential nursing skills and clinical preparation, allowing students to enter the workforce faster than traditional educational paths. By focusing on accelerated curriculum designs, these certificate and associate degree programs help address the growing healthcare workforce demands in South Carolina. Prospective students can explore options that minimize time investment while maximizing career potential in the nursing field.
School NameHighlightsRetention & Grad Rates
Northeastern Technical College
  • 48 semester hours total
  • Classroom and clinical training
  • Two semesters plus summer term
  • NCLEX-PN exam preparation
  • Competitive admissions process
  • Health sciences foundation
  • Nursing team concept training
  • Multiple healthcare settings
  • Graduation Rate: 35%
  • Retention Rate: 59%
  • Student to Faculty Ratio: 12:1
Galen Health Institutes-Myrtle Beach
  • 12 months full-time.
  • 21 months part-time.
  • Four start times yearly.
  • On-campus classes.
  • Prepares for NCLEX-PN exam.
  • Hands-on clinical training.
  • Supportive learning environment.
  • Fast-track to nursing career.
  • Retention Rate: 80%
  • Student to Faculty Ratio: 12:1
Orangeburg Calhoun Technical College
  • Diploma in Practical Nursing.
  • Hands-on learning experience.
  • Traditional and FLEX models available.
  • Prepares for various healthcare settings.
  • Specific admission requirements.
  • Accredited by ACEN.
  • High board pass rates.
  • Focus on real-life healthcare scenarios.
  • Graduation Rate: 40%
  • Retention Rate: 67%
  • Student to Faculty Ratio: 16:1
*Data source: NCES Integrated Postsecondary Education Data System, 2023.

Admission Requirements

High School Graduate
GPA of 2.5 or higher
Prerequisite Courses
Including: Biology, Medical Terminology
TEAS
Test of Essential Academic Skills Entrance Exam
Background Checks
Screening for patient safety.
CPR Certification
Preparedness to serve patients.
Immunization records
TB test results, proof of Hepatitis B vaccination and other required vaccines

Certification and Licensing

Certifying BoardSouth Carolina Board of Nursing, Department of Labor, Licensing and Regulation
CertificationNational Council Licensure Examination for Practical Nurses (NCLEX-PN) via Pearson VUE
Educational PrerequisiteGraduation from a Board-approved practical nursing program with official transcript and program verification
Application & Fees$70 licensure-by-exam application fee, $200 NCLEX exam fee, optional $10 temporary permit, fingerprint-based criminal background check required
Processing TimeAuthorization to Test issued in 1–2 weeks, permanent license typically granted within 14 business days after NCLEX passage and background clearance
License RenewalBiennial renewal every two years on April 30 of even-numbered years, $75 renewal fee
Continuing CompetencyComplete 30 contact hours of Board-approved continuing education or meet alternate competency pathways (certification, academic program, employer verification) each renewal cycle
Licensure by Endorsement$100 endorsement application fee, verification of a current unrestricted LPN license, fingerprint background check, proof of recent nursing practice or completion of a Board-approved refresher, optional $10 temporary permit.

Salary and Job Outlook

 The salary for Licensed Practical Nurses in South Carolina remains competitive and the job market outlook is positive. The average yearly salary of LPNs throughout South Carolina reaches $56,000 although it varies based on geographic area and work experience along with professional environment. New LPN graduates earn less money at first but their compensation increases throughout their career span as they gain experience and complete more education. The compensation of LPNs working in hospitals alongside specialty clinics grows through their shift work and overtime shifts. The LPN profession shows enduring employment opportunities because of rising demand for healthcare services that accompany an aging population. 

Salary & Career OutlookSouth CarolinaUSA
Avg Annual LVN Salary$53,817$62,340
Avg Hourly Wage$26.00$29.97
90th Percentile Salary>$77,575$80,510
Median Salary$53,422$62,340
10th Percentile Salary<$48,513$47,960
Projected Job Growth (2022–2032)~12%3%
Annual Job Openings~25,400~54,000

2026 Affordable LPN Program Options in South Carolina

Aspiring nurses in South Carolina have growing opportunities to enter the healthcare field through affordable Licensed Practical Nurse (LPN) programs. From Charleston to Columbia and across the Palmetto State, students can find cost-effective educational pathways that make professional training accessible. These certificate and associate degree programs provide essential healthcare training without breaking the bank, helping students minimize financial barriers to entering nursing. By focusing on budget-friendly options, students can pursue meaningful careers in medical settings while managing educational expenses. Carefully researching tuition ranges and program highlights allows prospective students to identify the most suitable and economical nursing education opportunities throughout South Carolina's diverse educational landscape.
School NameHighlightsAnnual Estimated Tuition & Fees
Midlands Technical College
  • Accredited nursing program
  • 44 total credit hours
  • Campus-based learning
  • Estimated cost $8,800
  • Multiple clinical settings
  • Prepare for NCLEX-PN exam
  • State Board of Nursing approved
  • Prerequisite courses required
  • $4,700 - $7,100 (Undergrad In-State)
  • $11,000 - $16,600 (Undergrad Non-Resident)
Tri-County Technical College
  • Diploma in Practical Nursing.
  • Eligible for financial aid.
  • Day and evening classes.
  • Face-to-face format.
  • Located at Easley Campus.
  • Focus on hands-on skills.
  • Prepares for immediate career entry.
  • Covers patient care essentials.
  • $4,800 - $7,200 (Undergrad In-State)
  • $8,900 - $13,300 (Undergrad Non-Resident)
Denmark Technical College
  • Campus-based program
  • GPA requirement: 2.50
  • Accuplacer Next Generation scores required
  • ATI TEAS Assessment proficiency
  • Includes anatomy and pharmacology
  • Hands-on clinical experience
  • Financial aid available
  • Scholarships for eligible students
  • $5,000 - $7,600 (Undergrad In-State)
  • $9,500 - $14,300 (Undergrad Non-Resident)
*Data source: NCES, IPEDS 2023 institutional survey.

Advancement Pathways

 The LPN license provides an excellent starting point for nurses who want to build their careers in nursing practice. Most LPNs in South Carolina pursue LPN-to-RN bridge programs after their education to become registered nurses by completing extra training. Prior coursework and experience typically earn credit through these programs thus students need less time to earn their associate degree in nursing. Some colleges enable students to enroll in bridge programs through flexible class schedules that include evening or part-time study. LPNs can earn specialized certifications through education in IV therapy, wound care, and gerontology which improve their skills and increase their compensation. LPNs who have gained experience can move into leadership positions as team leads or charge nurses in nursing facilities that provide long-term care. Most employers support continuing education and encourage their staff to pursue it. The educational pathways help nurses advance in their careers and improve their satisfaction while also expanding their professional opportunities within the ever-evolving healthcare sector.

List of LPN Programs in South Carolina

Jump to City:

Beaufort, SC

Technical College of the Lowcountry

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • Campus-based program
    • Prepares for NCLEX-PN exam
    • Hands-on patient care training
    • Located in Beaufort, SC
    • High school diploma required

Charleston, SC

Trident Technical College

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • Three-semester nursing program
    • 43 total credit hours
    • NCLEX-PN exam preparation
    • Clinical practice included
    • Potential ADN progression
    • Multiple admission pathways
    • Accredited nursing program

Cheraw, SC

Northeastern Technical College

  • Certificate/Diploma - Applied Science - Practical Nursing

    Campus Based - Website

    • 48 semester hours total
    • Classroom and clinical training
    • Two semesters plus summer term
    • NCLEX-PN exam preparation
    • Competitive admissions process
    • Health sciences foundation
    • Nursing team concept training
    • Multiple healthcare settings

Conway, SC

Horry-Georgetown Technical College

  • Certificate/Diploma - Nursing - PN Diploma

    Campus Based - Website

    • 48 total credit hours
    • Clinical experience included
    • Prepare for NCLEX-PN exam
    • Multiple campus locations
    • Accredited nursing program
    • Diverse healthcare career paths
    • Comprehensive admission requirements
    • Patient-centered care focus

Denmark, SC

Denmark Technical College

  • Certificate/Diploma - Diploma in Practical Nursing

    Campus Based - Website

    • Campus-based program
    • GPA requirement: 2.50
    • Accuplacer Next Generation scores required
    • ATI TEAS Assessment proficiency
    • Includes anatomy and pharmacology
    • Hands-on clinical experience
    • Financial aid available
    • Scholarships for eligible students

Florence, SC

Florence-Darlington Technical College

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • 16-month diploma program
    • 48 total credit hours
    • NCLEX-PN licensure preparation
    • Day program schedule
    • Nursing & Allied Health division
    • TEAS test required
    • Biology prerequisite needed
    • Minimum 2.0 GPA

Graniteville, SC

Aiken Technical College

  • Certificate/Diploma - Diploma in Practical Nursing

    Campus Based - Website

    • Accredited nursing program.
    • Prepares for NCLEX-PN exam.
    • Hands-on clinical experience.
    • Flexible scheduling options.
    • Focus on patient care.
    • Entry-level nursing preparation.
    • Opportunities for career advancement.
    • Supervised clinical work.

Greenwood, SC

Piedmont Technical College

  • Certificate/Diploma - Practical Nursing, D.A.S.

    Campus Based - Website

    • Three-semester nursing program
    • NCLEX-PN exam preparation
    • 46 total credit hours
    • Competitive admission process
    • Multiple campus start options
    • Comprehensive clinical training
    • Pathway to advanced nursing
    • Diverse healthcare settings

Kingstree, SC

Williamsburg Technical College

  • Certificate/Diploma - Diploma – Health Science Practical Nursing

    Campus Based - Website

    • 40-week program duration.
    • 48 credit hours required.
    • Campus-based learning.
    • TEAS exam score of 60+ needed.
    • GPA requirement of 2.0.
    • NCLEX-PN exam eligibility.
    • Clinical experience included.
    • Hands-on learning focus.

Myrtle Beach, SC

Galen Health Institutes-Myrtle Beach

  • Certificate/Diploma - Practical/Vocational Nursing

    Campus Based - Website

    • 12 months full-time.
    • 21 months part-time.
    • Four start times yearly.
    • On-campus classes.
    • Prepares for NCLEX-PN exam.
    • Hands-on clinical training.
    • Supportive learning environment.
    • Fast-track to nursing career.

Orangeburg, SC

Orangeburg Calhoun Technical College

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • Diploma in Practical Nursing.
    • Hands-on learning experience.
    • Traditional and FLEX models available.
    • Prepares for various healthcare settings.
    • Specific admission requirements.
    • Accredited by ACEN.
    • High board pass rates.
    • Focus on real-life healthcare scenarios.

Pendleton, SC

Tri-County Technical College

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • Diploma in Practical Nursing.
    • Eligible for financial aid.
    • Day and evening classes.
    • Face-to-face format.
    • Located at Easley Campus.
    • Focus on hands-on skills.
    • Prepares for immediate career entry.
    • Covers patient care essentials.

Rock Hill, SC

York Technical College

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • Accredited Nursing Program
    • NCLEX-RN Exam Preparation
    • Diverse Clinical Rotation Experiences
    • Located on Chester Campus
    • Limited Enrollment Program
    • Multiple Admission Tracks
    • Comprehensive Clinical Requirements
    • Flexible Clinical Scheduling

Spartanburg, SC

Spartanburg Community College

  • Certificate/Diploma - Practical Nursing Diploma

    Campus Based - Website

    • Campus-based program.
    • Prepares for beginning-level nursing.
    • Under RN or physician supervision.
    • ACEN accreditation candidacy.
    • Focuses on practical nursing skills.

Sumter, SC

Central Carolina Technical College

  • Certificate/Diploma - Practical Nursing

    Campus Based - Website

    • 48 semester hours
    • Prepares for NCLEX-PN
    • Approved by SC Board of Nursing
    • Candidate for ACEN accreditation
    • Hands-on clinical experience
    • Focuses on critical thinking
    • Technology in nursing care
    • Caring for diverse populations

West Columbia, SC

Midlands Technical College

  • Certificate/Diploma - Practical Nursing (LPN)

    Campus Based - Website

    • Accredited nursing program
    • 44 total credit hours
    • Campus-based learning
    • Estimated cost $8,800
    • Multiple clinical settings
    • Prepare for NCLEX-PN exam
    • State Board of Nursing approved
    • Prerequisite courses required
*Reference: U.S. DOE, NCES, IPEDS 2023 data release.